Which drug is a carbonic anhydrase inhibitor?

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Study for the NBEO Part II TMOD Exam. Prepare with flashcards and multiple choice questions, each with hints and explanations. Get ready for your exam!

Multiple Choice

Which drug is a carbonic anhydrase inhibitor?

Explanation:
Carbonic anhydrase inhibitors lower intraocular pressure by blocking the enzyme in the ciliary body that helps form aqueous humor, reducing production of aqueous humor. Dorzolamide is a topical carbonic anhydrase inhibitor used to treat glaucoma. The other drugs work by different mechanisms: beta blockers decrease aqueous production through adrenergic blockade, prostaglandin analogs like latanoprost increase outflow, and alpha-2 agonists like brimonidine reduce production and can modestly increase outflow. So dorzolamide is the one that directly inhibits carbonic anhydrase.

Carbonic anhydrase inhibitors lower intraocular pressure by blocking the enzyme in the ciliary body that helps form aqueous humor, reducing production of aqueous humor. Dorzolamide is a topical carbonic anhydrase inhibitor used to treat glaucoma. The other drugs work by different mechanisms: beta blockers decrease aqueous production through adrenergic blockade, prostaglandin analogs like latanoprost increase outflow, and alpha-2 agonists like brimonidine reduce production and can modestly increase outflow. So dorzolamide is the one that directly inhibits carbonic anhydrase.

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