Which antihypertensive class is least likely to cause a cough?

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Study for the NBEO Part II TMOD Exam. Prepare with flashcards and multiple choice questions, each with hints and explanations. Get ready for your exam!

Multiple Choice

Which antihypertensive class is least likely to cause a cough?

Explanation:
Cough from antihypertensives is most commonly due to ACE inhibitors, which increase bradykinin by blocking its breakdown. ARBs, on the other hand, block the angiotensin II receptor without affecting bradykinin, so bradykinin doesn’t accumulate and the cough is unlikely. Beta-blockers and thiazide diuretics aren’t typically associated with a cough, while ACE inhibitors are the classic culprits. So ARBs are the least likely to cause a cough. If a patient develops a cough on an ACE inhibitor, switching to an ARB can help, with attention to other risks like hyperkalemia and kidney function.

Cough from antihypertensives is most commonly due to ACE inhibitors, which increase bradykinin by blocking its breakdown. ARBs, on the other hand, block the angiotensin II receptor without affecting bradykinin, so bradykinin doesn’t accumulate and the cough is unlikely. Beta-blockers and thiazide diuretics aren’t typically associated with a cough, while ACE inhibitors are the classic culprits. So ARBs are the least likely to cause a cough. If a patient develops a cough on an ACE inhibitor, switching to an ARB can help, with attention to other risks like hyperkalemia and kidney function.

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