Which agent increases trabecular meshwork outflow?

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Study for the NBEO Part II TMOD Exam. Prepare with flashcards and multiple choice questions, each with hints and explanations. Get ready for your exam!

Multiple Choice

Which agent increases trabecular meshwork outflow?

Explanation:
Pilocarpine increases trabecular meshwork outflow by stimulating muscarinic receptors, which causes contraction of the ciliary muscle. This action opens the angle and widens the spaces in the trabecular meshwork, boosting drainage through Schlemm’s canal (the conventional outflow pathway). The other drugs work differently: timolol and dorzolamide reduce aqueous humor production, while latanoprost mainly increases outflow through the uveoscleral pathway rather than the trabecular meshwork.

Pilocarpine increases trabecular meshwork outflow by stimulating muscarinic receptors, which causes contraction of the ciliary muscle. This action opens the angle and widens the spaces in the trabecular meshwork, boosting drainage through Schlemm’s canal (the conventional outflow pathway). The other drugs work differently: timolol and dorzolamide reduce aqueous humor production, while latanoprost mainly increases outflow through the uveoscleral pathway rather than the trabecular meshwork.

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