Which adverse effects are commonly associated with Diamox (acetazolamide)?

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Study for the NBEO Part II TMOD Exam. Prepare with flashcards and multiple choice questions, each with hints and explanations. Get ready for your exam!

Multiple Choice

Which adverse effects are commonly associated with Diamox (acetazolamide)?

Explanation:
Diamox (acetazolamide) inhibits carbonic anhydrase in the proximal tubule, which reduces bicarbonate reabsorption. The resulting loss of bicarbonate in the urine leads to a non-anion gap metabolic acidosis and can be accompanied by related electrolyte disturbances. A commonly reported, distinctive side effect is a metallic taste (taste disturbance). This combination—metabolic acidosis and metallic taste—fits the drug’s mechanism and its well-known adverse effects. Other listed effects don’t align with acetazolamide’s typical profile (tinnitus/deafness, insomnia/t tremor, or hyperglycemia/weight gain are not characteristic).

Diamox (acetazolamide) inhibits carbonic anhydrase in the proximal tubule, which reduces bicarbonate reabsorption. The resulting loss of bicarbonate in the urine leads to a non-anion gap metabolic acidosis and can be accompanied by related electrolyte disturbances. A commonly reported, distinctive side effect is a metallic taste (taste disturbance). This combination—metabolic acidosis and metallic taste—fits the drug’s mechanism and its well-known adverse effects. Other listed effects don’t align with acetazolamide’s typical profile (tinnitus/deafness, insomnia/t tremor, or hyperglycemia/weight gain are not characteristic).

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