Phenytoin toxicity can cause which ocular sign during a dilated exam?

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Study for the NBEO Part II TMOD Exam. Prepare with flashcards and multiple choice questions, each with hints and explanations. Get ready for your exam!

Multiple Choice

Phenytoin toxicity can cause which ocular sign during a dilated exam?

Explanation:
Phenytoin toxicity commonly disrupts eye-movement control, producing nystagmus as a hallmark finding on a dilated exam. The drug’s CNS effects, especially on cerebellar and vestibular pathways, lead to rhythmic, involuntary eye movements that are typically horizontal. Diplopia can occur with significant impairment, but nystagmus is the most reliable and characteristic sign of toxicity. Retinal detachment and anisocoria are not associated with phenytoin toxicity.

Phenytoin toxicity commonly disrupts eye-movement control, producing nystagmus as a hallmark finding on a dilated exam. The drug’s CNS effects, especially on cerebellar and vestibular pathways, lead to rhythmic, involuntary eye movements that are typically horizontal. Diplopia can occur with significant impairment, but nystagmus is the most reliable and characteristic sign of toxicity. Retinal detachment and anisocoria are not associated with phenytoin toxicity.

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