Combigan is a combination glaucoma medication. Which two drugs constitute this product?

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Study for the NBEO Part II TMOD Exam. Prepare with flashcards and multiple choice questions, each with hints and explanations. Get ready for your exam!

Multiple Choice

Combigan is a combination glaucoma medication. Which two drugs constitute this product?

Explanation:
Combigan combines two agents with complementary actions to lower intraocular pressure: timolol, a nonselective beta-blocker that mainly reduces aqueous humor production, and brimonidine, an alpha-2 adrenergic agonist that also decreases production and can modestly increase outflow. This pairing provides a greater IOP reduction than either drug alone and is delivered as a fixed-dose combination for convenience. The other listed pairings involve different drugs (such as dorzolamide or pilocarpine) that are not components of Combigan, which is specifically timolol plus brimonidine.

Combigan combines two agents with complementary actions to lower intraocular pressure: timolol, a nonselective beta-blocker that mainly reduces aqueous humor production, and brimonidine, an alpha-2 adrenergic agonist that also decreases production and can modestly increase outflow. This pairing provides a greater IOP reduction than either drug alone and is delivered as a fixed-dose combination for convenience. The other listed pairings involve different drugs (such as dorzolamide or pilocarpine) that are not components of Combigan, which is specifically timolol plus brimonidine.

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